Magnetic Resonance
Magnetic Resonance
MR
Articles | Volume 1, issue 1
Articles | Volume 1, issue 1
https://doi.org/10.5194/mr-1-27-2020
© Author(s) 2020. This work is distributed under
the Creative Commons Attribution 4.0 License.
https://doi.org/10.5194/mr-1-27-2020
© Author(s) 2020. This work is distributed under
the Creative Commons Attribution 4.0 License.
Articles | Volume 1, issue 1
Research article
 | 
28 Feb 2020
Research article |  | 28 Feb 2020

Transferring principles of solid-state and Laplace NMR to the field of in vivo brain MRI

João P. de Almeida Martins, Chantal M. W. Tax, Filip Szczepankiewicz, Derek K. Jones, Carl-Fredrik Westin, and Daniel Topgaard

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Short summary
Detailed interpretation of brain MRI data is hampered by the fact that each imaging voxel comprises several types of cells and tissues. To address this, we adapt signal encoding and data inversion strategies from solid-state and low-field NMR to quantify the sub-voxel heterogeneity of the human brain with 5D relaxation–diffusion distributions wherein distinct tissue components are resolved, individually characterized, and subsequently mapped throughout the volume of the brain.
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