Fragile protein folds: sequence and environmental factors affecting the equilibrium of two  interconverting, stably folded  protein conformations

Xu, Xingjian; Dikiy, Igor; Evans, Matthew R.; Marcelino, Leandro P.; Gardner, Kevin H.

doi:https://doi.org/10.5194/mr-2-63-2021

Articles | Volume 2, issue 1

https://doi.org/10.5194/mr-2-63-2021

© Author(s) 2021. This work is distributed under
the Creative Commons Attribution 4.0 License.

Special issue:

Robert Kaptein Festschrift

https://doi.org/10.5194/mr-2-63-2021

© Author(s) 2021. This work is distributed under
the Creative Commons Attribution 4.0 License.

Articles | Volume 2, issue 1

Research article

|

10 Mar 2021

Research article |

| 10 Mar 2021

Fragile protein folds: sequence and environmental factors affecting the equilibrium of two interconverting, stably folded protein conformations

Xingjian Xu, Igor Dikiy, Matthew R. Evans, Leandro P. Marcelino, and Kevin H. Gardner

Supplement

https://doi.org/10.5194/mr-2-63-2021-supplement

Data sets

Backbone chemical shift assignments of ARNT PAS-B in 8M urea Xu, X., Dikiy, I., Evans, M.R., Marcelino, L.P., Gardner, K.H. https://doi.org/10.13018/BMR50761

Backbone chemical shift assignments of ARNT PAS-B F444Q/F446A/Y456T in 8M urea Xu, X., Dikiy, I., Evans, M.R., Marcelino, L.P., Gardner, K.H. https://doi.org/10.13018/BMR50762

Backbone chemical shift assignments of ARNT PAS-B Y456T in 8M urea Xu, X., Dikiy, I., Evans, M.R., Marcelino, L.P., Gardner, K.H. https://doi.org/10.13018/BMR50763

Short summary

While most proteins adopt one conformation, several interconvert between two or more very...