Articles | Volume 1, issue 1
https://doi.org/10.5194/mr-1-59-2020
https://doi.org/10.5194/mr-1-59-2020
Research article
 | 
12 May 2020
Research article |  | 12 May 2020

Optimising broadband pulses for DEER depends on concentration and distance range of interest

Andreas Scherer, Sonja Tischlik, Sabrina Weickert, Valentin Wittmann, and Malte Drescher

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Cited articles

Abdullin, D., Duthie, F., Meyer, A., Müller, E. S., Hagelueken, G., and Schiemann, O.: Comparison of PELDOR and RIDME for Distance Measurements between Nitroxides and Low-Spin Fe(III) Ions, J. Phys. Chem. B, 119, 13534–13542, https://doi.org/10.1021/acs.jpcb.5b02118, 2015. 
Bahrenberg, T., Rosenski, Y., Carmieli, R., Zibzener, K., Qi, M., Frydman, V., Godt, A., Goldfarb, D., and Feintuch, A.: Improved sensitivity for W-band Gd(III)-Gd(III) and nitroxide-nitroxide DEER measurements with shaped pulses, J. Magn. Reson., 283, 1–13, https://doi.org/10.1016/j.jmr.2017.08.003, 2017. 
Baum, J., Tycko, R., and Pines, A.: Broadband and adiabatic inversion of a two-level system by phase-modulated pulses, Phys. Rev. A, 32, 3435–3447, 1985. 
Böhlen, J.-M. and Bodenhausen, G.: Experimental Aspects of Chirp NMR Spectroscopy, J. Magn. Reson. A, 102, 293–301, https://doi.org/10.1006/jmra.1993.1107, 1993. 
Borbat, P. P., Georgieva, E. R., and Freed, J. H.: Improved Sensitivity for Long-Distance Measurements in Biomolecules: Five-Pulse Double Electron–Electron Resonance, J. Phys. Chem. Lett., 4, 170–175, https://doi.org/10.1021/jz301788n, 2013. 
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Short summary
The determination of distance distributions in the nanometre range is an important application of pulsed electron paramagnetic resonance spectroscopy. However, low sensitivity is often a major challenge. In this paper, we compare several broadband-shaped pulses and compare their performance to classical rectangular pulses in order to increase the sensitivity of double electron–electron resonance to a commercial setup. We show that improvements in sensitivity of up to 86 % are possible.