Real-time nuclear magnetic resonance spectroscopy in the study of biomolecular kinetics and dynamics
György Pintér,Katharina F. Hohmann,J. Tassilo Grün,Julia Wirmer-Bartoschek,Clemens Glaubitz,Boris Fürtig,and Harald Schwalbe
György Pintér
Institute for Organic Chemistry and Chemical Biology, Center for
Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang
Goethe-Universität Frankfurt, Frankfurt 60438, Germany
Katharina F. Hohmann
Institute for Organic Chemistry and Chemical Biology, Center for
Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang
Goethe-Universität Frankfurt, Frankfurt 60438, Germany
J. Tassilo Grün
Institute for Organic Chemistry and Chemical Biology, Center for
Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang
Goethe-Universität Frankfurt, Frankfurt 60438, Germany
Julia Wirmer-Bartoschek
Institute for Organic Chemistry and Chemical Biology, Center for
Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang
Goethe-Universität Frankfurt, Frankfurt 60438, Germany
Clemens Glaubitz
Institute for Biophysical Chemistry, Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-Universität Frankfurt, Frankfurt 60438, Germany
Institute for Organic Chemistry and Chemical Biology, Center for
Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang
Goethe-Universität Frankfurt, Frankfurt 60438, Germany
Institute for Organic Chemistry and Chemical Biology, Center for
Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang
Goethe-Universität Frankfurt, Frankfurt 60438, Germany
Viewed
Total article views: 5,124 (including HTML, PDF, and XML)
HTML
PDF
XML
Total
BibTeX
EndNote
3,221
1,810
93
5,124
101
130
HTML: 3,221
PDF: 1,810
XML: 93
Total: 5,124
BibTeX: 101
EndNote: 130
Views and downloads (calculated since 10 Feb 2021)
Cumulative views and downloads
(calculated since 10 Feb 2021)
Total article views: 3,910 (including HTML, PDF, and XML)
HTML
PDF
XML
Total
BibTeX
EndNote
2,736
1,100
74
3,910
86
120
HTML: 2,736
PDF: 1,100
XML: 74
Total: 3,910
BibTeX: 86
EndNote: 120
Views and downloads (calculated since 11 May 2021)
Cumulative views and downloads
(calculated since 11 May 2021)
Total article views: 1,214 (including HTML, PDF, and XML)
HTML
PDF
XML
Total
BibTeX
EndNote
485
710
19
1,214
15
10
HTML: 485
PDF: 710
XML: 19
Total: 1,214
BibTeX: 15
EndNote: 10
Views and downloads (calculated since 10 Feb 2021)
Cumulative views and downloads
(calculated since 10 Feb 2021)
Viewed (geographical distribution)
Total article views: 5,124 (including HTML, PDF, and XML)
Thereof 4,662 with geography defined
and 462 with unknown origin.
Total article views: 3,910 (including HTML, PDF, and XML)
Thereof 3,641 with geography defined
and 269 with unknown origin.
Total article views: 1,214 (including HTML, PDF, and XML)
Thereof 1,021 with geography defined
and 193 with unknown origin.
The folding, refolding and misfolding of biomacromolecules including proteins, DNA and RNA is an important area of biophysical research to understand functional and disease states of a cell. NMR spectroscopy provides detailed insight, with both high time and atomic resolution. These experiments put stringent requirements on signal-to-noise for often irreversible folding reactions. The review describes methodological approaches and highlights key applications.
The folding, refolding and misfolding of biomacromolecules including proteins, DNA and RNA is an...
