Real-time nuclear magnetic resonance spectroscopy in the study of biomolecular kinetics and dynamics
György Pintér,Katharina F. Hohmann,J. Tassilo Grün,Julia Wirmer-Bartoschek,Clemens Glaubitz,Boris Fürtig,and Harald Schwalbe
György Pintér
Institute for Organic Chemistry and Chemical Biology, Center for
Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang
Goethe-Universität Frankfurt, Frankfurt 60438, Germany
Katharina F. Hohmann
Institute for Organic Chemistry and Chemical Biology, Center for
Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang
Goethe-Universität Frankfurt, Frankfurt 60438, Germany
J. Tassilo Grün
Institute for Organic Chemistry and Chemical Biology, Center for
Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang
Goethe-Universität Frankfurt, Frankfurt 60438, Germany
Julia Wirmer-Bartoschek
Institute for Organic Chemistry and Chemical Biology, Center for
Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang
Goethe-Universität Frankfurt, Frankfurt 60438, Germany
Clemens Glaubitz
Institute for Biophysical Chemistry, Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-Universität Frankfurt, Frankfurt 60438, Germany
Institute for Organic Chemistry and Chemical Biology, Center for
Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang
Goethe-Universität Frankfurt, Frankfurt 60438, Germany
Institute for Organic Chemistry and Chemical Biology, Center for
Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang
Goethe-Universität Frankfurt, Frankfurt 60438, Germany
Viewed
Total article views: 2,449 (including HTML, PDF, and XML)
HTML
PDF
XML
Total
BibTeX
EndNote
1,481
927
41
2,449
37
29
HTML: 1,481
PDF: 927
XML: 41
Total: 2,449
BibTeX: 37
EndNote: 29
Views and downloads (calculated since 10 Feb 2021)
Cumulative views and downloads
(calculated since 10 Feb 2021)
Total article views: 1,602 (including HTML, PDF, and XML)
HTML
PDF
XML
Total
BibTeX
EndNote
1,056
518
28
1,602
31
25
HTML: 1,056
PDF: 518
XML: 28
Total: 1,602
BibTeX: 31
EndNote: 25
Views and downloads (calculated since 11 May 2021)
Cumulative views and downloads
(calculated since 11 May 2021)
Total article views: 847 (including HTML, PDF, and XML)
HTML
PDF
XML
Total
BibTeX
EndNote
425
409
13
847
6
4
HTML: 425
PDF: 409
XML: 13
Total: 847
BibTeX: 6
EndNote: 4
Views and downloads (calculated since 10 Feb 2021)
Cumulative views and downloads
(calculated since 10 Feb 2021)
Viewed (geographical distribution)
Total article views: 2,449 (including HTML, PDF, and XML)
Thereof 2,100 with geography defined
and 349 with unknown origin.
Total article views: 1,602 (including HTML, PDF, and XML)
Thereof 1,426 with geography defined
and 176 with unknown origin.
Total article views: 847 (including HTML, PDF, and XML)
Thereof 674 with geography defined
and 173 with unknown origin.
The folding, refolding and misfolding of biomacromolecules including proteins, DNA and RNA is an important area of biophysical research to understand functional and disease states of a cell. NMR spectroscopy provides detailed insight, with both high time and atomic resolution. These experiments put stringent requirements on signal-to-noise for often irreversible folding reactions. The review describes methodological approaches and highlights key applications.
The folding, refolding and misfolding of biomacromolecules including proteins, DNA and RNA is an...