PRESERVE: adding variable flip-angle excitation to transverse relaxation-optimized NMR spectroscopy

Brutscher, Bernhard

doi:https://doi.org/10.5194/mr-5-131-2024

Articles | Volume 5, issue 2

https://doi.org/10.5194/mr-5-131-2024

© Author(s) 2024. This work is distributed under
the Creative Commons Attribution 4.0 License.

https://doi.org/10.5194/mr-5-131-2024

© Author(s) 2024. This work is distributed under
the Creative Commons Attribution 4.0 License.

Articles | Volume 5, issue 2

Research article

|

12 Sep 2024

Research article |

| 12 Sep 2024

PRESERVE: adding variable flip-angle excitation to transverse relaxation-optimized NMR spectroscopy

Bernhard Brutscher

Supplement

https://doi.org/10.5194/mr-5-131-2024-supplement

Data sets

NMR data sets Bernhard Brutscher https://doi.org/10.5281/zenodo.11447367

Short summary

We introduce the PRESERVE pulse sequence element, allowing variable flip-angle adjustment in 2D ¹H–¹⁵N and ¹H–¹³C transverse-relaxation-optimized-spectroscopy (TROSY)-type correlation experiments. PRESERVE-TROSY exploits a remarkable array of up to nine orthogonal polarization-coherence transfer pathways, showcasing the remarkable potential of spin manipulations achievable via the design and optimization of nuclear magnetic resonance (NMR) pulse sequences.