Articles | Volume 6, issue 2
https://doi.org/10.5194/mr-6-211-2025
https://doi.org/10.5194/mr-6-211-2025
Research article
 | 
12 Aug 2025
Research article |  | 12 Aug 2025

Can label or protein deuteration extend the phase relaxation time of Gd(III) spin labels?

Elena Edinach, Xing Zhang, Chao-Yu Cui, Yin Yang, George Mitrikas, Alexey Bogdanov, Xun-Cheng Su, and Daniella Goldfarb

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Short summary
Protein structure and motion are key to its function. Using electron paramagnetic resonance (EPR) methods, it is possible to measure distances between magnetic markers like gadolinium ions grafted on proteins. Such measurements rely on the gadolinium phase memory time, determining how long the signal lasts. We studied how nearby atoms and environmental noise affect signal lifetimes using advanced EPR techniques. Our findings show how lifetimes can be extended to design better protein analysis.
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