Magnetic Resonance
Magnetic Resonance
MR
Articles | Volume 7, issue 1
Articles | Volume 7, issue 1
https://doi.org/10.5194/mr-7-29-2026
© Author(s) 2026. This work is distributed under
the Creative Commons Attribution 4.0 License.
https://doi.org/10.5194/mr-7-29-2026
© Author(s) 2026. This work is distributed under
the Creative Commons Attribution 4.0 License.
Articles | Volume 7, issue 1
Research article
 | 
16 Apr 2026
Research article |  | 16 Apr 2026

Accelerated 19F biomolecular magic-angle spinning NMR with paramagnetic dopants

Lea M. Becker, Giorgia Toscano, Anna Kapitonova, Rajkumar Singh, Undina Guillerm, Roman J. Lichtenecker, and Paul Schanda

Viewed

Total article views: 311 (including HTML, PDF, and XML)
HTML PDF XML Total Supplement BibTeX EndNote
216 74 21 311 44 14 14
  • HTML: 216
  • PDF: 74
  • XML: 21
  • Total: 311
  • Supplement: 44
  • BibTeX: 14
  • EndNote: 14
Views and downloads (calculated since 24 Feb 2026)
Cumulative views and downloads (calculated since 24 Feb 2026)

Viewed (geographical distribution)

Total article views: 311 (including HTML, PDF, and XML) Thereof 311 with geography defined and 0 with unknown origin.
Country # Views %
  • 1
1
 
 
 
 
Latest update: 16 Apr 2026
Download
Short summary
Magic-angle-spinning nuclear magnetic resonance (NMR) is ideal for studying protein structure and dynamics. Introducing fluorine atoms offers advantages due to the NMR properties of 19F and the absence of natural fluorine. However, the slow spin polarisation recovery of 19F causes long recycle delays between scans. We demonstrate that adding paramagnetic co-solutes to solid protein samples largely accelerates these experiments, and we identify optimal conditions for this approach.
Read more
Share