Increased flow rate of hyperpolarized aqueous solution for dynamic nuclear polarization-enhanced magnetic resonance imaging achieved by an open Fabry–Pérot type microwave resonator

Fedotov, Alexey; Kurakin, Ilya; Fischer, Sebastian; Vogl, Thomas; Prisner, Thomas F.; Denysenkov, Vasyl

doi:https://doi.org/10.5194/mr-1-275-2020

Articles | Volume 1, issue 2

https://doi.org/10.5194/mr-1-275-2020

© Author(s) 2020. This work is distributed under
the Creative Commons Attribution 4.0 License.

Special issue:

Robert Kaptein Festschrift

https://doi.org/10.5194/mr-1-275-2020

© Author(s) 2020. This work is distributed under
the Creative Commons Attribution 4.0 License.

Articles | Volume 1, issue 2

Research article

|

18 Nov 2020

Research article |

| 18 Nov 2020

Increased flow rate of hyperpolarized aqueous solution for dynamic nuclear polarization-enhanced magnetic resonance imaging achieved by an open Fabry–Pérot type microwave resonator

Alexey Fedotov, Ilya Kurakin, Sebastian Fischer, Thomas Vogl, Thomas F. Prisner, and Vasyl Denysenkov

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Final revised paper (published on 18 Nov 2020)
Supplement to the final revised paper
Preprint (discussion started on 01 Sep 2020)

Interactive discussion

Status: closed

AC: Author comment | RC: Referee comment | SC: Short comment | EC: Editor comment

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- Supplement

RC1: 'Comments', Anonymous Referee #1, 15 Sep 2020
RC2: 'Increased flow rate of hyperpolarized aqueous solution for DNP-enhanced MRI achieved by an open Fabry-Pérot type microwave resonator', Anonymous Referee #2, 21 Sep 2020
AC1: 'Response to Reviewer comments and suggestions', Thomas Prisner, 07 Oct 2020

Peer-review completion

AR: Author's response | RR: Referee report | ED: Editor decision

AR by Thomas Prisner on behalf of the Authors (07 Oct 2020) Author's response Manuscript

ED: Publish as is (13 Oct 2020) by Konstantin Ivanov (deceased)

AR by Thomas Prisner on behalf of the Authors (16 Oct 2020) Author's response Manuscript

Post-review adjustments

AA: Author's adjustment | EA: Editor approval

AA by Thomas Prisner on behalf of the Authors (03 Nov 2020) Author's adjustment Manuscript

EA: Adjustments approved (06 Nov 2020) by Konstantin Ivanov (deceased)

Short summary

The sensitivity of magnetic resonance imaging can be increased by coupling of the less sensitive nuclear spins which are excited at radio frequencies to unpaired electron spins of radicals which are excited at microwave frequencies. Here we demonstrate how a Fabry–Perot-type microwave resonance structure can be used to significantly enhance the polarization transfer from electron to water proton nuclear spins under constant flow conditions for imaging applications at 1.5 T.