Magnetic Resonance
Magnetic Resonance
MR
Articles | Volume 1, issue 2
Articles | Volume 1, issue 2
https://doi.org/10.5194/mr-1-275-2020
© Author(s) 2020. This work is distributed under
the Creative Commons Attribution 4.0 License.
Special issue:
https://doi.org/10.5194/mr-1-275-2020
© Author(s) 2020. This work is distributed under
the Creative Commons Attribution 4.0 License.
Articles | Volume 1, issue 2
Research article
 | 
18 Nov 2020
Research article |  | 18 Nov 2020

Increased flow rate of hyperpolarized aqueous solution for dynamic nuclear polarization-enhanced magnetic resonance imaging achieved by an open Fabry–Pérot type microwave resonator

Alexey Fedotov, Ilya Kurakin, Sebastian Fischer, Thomas Vogl, Thomas F. Prisner, and Vasyl Denysenkov

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Cited articles

Albert, M. S. and Balamore, D.: Development of hyperpolarized noble gas MRI, Nucl. Instrum. Methods, A402, 441–453, https://doi.org/10.1016/S0168-9002(97)00888-7, 1998. 
Andryieuski, A., Kuznetsova, S. M., Zhukovsky, S. V., Kivshar, Y. S., and Lavrinenko, A. V.: Water: promising opportunities for tunable all-dielectric electromagnetic metamaterials, Sci. Rep., 5, 13535, https://doi.org/10.1038/srep13535, 2015. 
Ardenkjaer-Larsen, J. H., Laustsen, C., Bowen, S., and Rizi, R.: Hyperpolarized H2O angiography, Magn. Reson. Med., 71, 50–56, https://doi.org/10.1002/mrm.25033, 2014. 
Barnes, J. P. and Freed, J. H.: Aqueous sample holders for high-frequency electron spin resonance, Rev. Sci. Instrum., 68, 2838–2846, https://doi.org/10.1063/1.1148205, 1997. 
Belousov, V., Denisov, G., and Chirkov, A.: Calculation and parameter-control methods of eigenmodes of the simplest two-mirror resonators, Izv. Vuzov, Radiophys., 8, 738–746, https://doi.org/10.1023/A:1004869622320, 2000. 
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The sensitivity of magnetic resonance imaging can be increased by coupling of the less sensitive nuclear spins which are excited at radio frequencies to unpaired electron spins of radicals which are excited at microwave frequencies. Here we demonstrate how a Fabry–Perot-type microwave resonance structure can be used to significantly enhance the polarization transfer from electron to water proton nuclear spins under constant flow conditions for imaging applications at 1.5 T.
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