Overhauser dynamic nuclear polarization (ODNP)-enhanced two-dimensional proton NMR spectroscopy at low magnetic fields

Keller, Timothy J.; Maly, Thorsten

doi:https://doi.org/10.5194/mr-2-117-2021

Articles | Volume 2, issue 1

https://doi.org/10.5194/mr-2-117-2021

© Author(s) 2021. This work is distributed under
the Creative Commons Attribution 4.0 License.

https://doi.org/10.5194/mr-2-117-2021

© Author(s) 2021. This work is distributed under
the Creative Commons Attribution 4.0 License.

Articles | Volume 2, issue 1

Research article

|

12 Apr 2021

Research article |

| 12 Apr 2021

Overhauser dynamic nuclear polarization (ODNP)-enhanced two-dimensional proton NMR spectroscopy at low magnetic fields

Timothy J. Keller and Thorsten Maly

Supplement

https://doi.org/10.5194/mr-2-117-2021-supplement

Data sets

2D_ODNP_Spectroscopy_DataRep Timothy Keller and Thorsten Maly https://github.com/Bridge12Technologies/2D_ODNP_Spectroscopy_DataRep

Overhauser Dynamic Nuclear Polarization Enhanced Two-Dimensional Proton NMR Spectroscopy at Low Magnetic Fields Timothy J. Keller and Thorsten Maly https://doi.org/10.5281/zenodo.4479048

Model code and software

DNPLab/DNPLab (Version 2DODNPPaper) Timothy Keller, Thomas Casey, Yanxian Lin, Thorsten Maly, and John M. Franck https://doi.org/10.5281/zenodo.4670553

Short summary

Typically, low-field Overhauser dynamic nuclear polarization (ODNP) experiments are 1D NMR experiments to study hydration dynamics. Here, we demonstrate the application of ODNP-enhanced 2D J-resolved (JRES) spectroscopy to improve spectral resolution beyond the limit imposed by the line broadening introduced by the paramagnetic polarizing agent. Crucial to these experiments is interleaved spectral referencing to compensate for temperature-induced field drifts over the course of the experiment.