Articles | Volume 2, issue 1
Magn. Reson., 2, 117–128, 2021
https://doi.org/10.5194/mr-2-117-2021
Magn. Reson., 2, 117–128, 2021
https://doi.org/10.5194/mr-2-117-2021

Research article 12 Apr 2021

Research article | 12 Apr 2021

Overhauser dynamic nuclear polarization (ODNP)-enhanced two-dimensional proton NMR spectroscopy at low magnetic fields

Timothy J. Keller and Thorsten Maly

Related subject area

Field: Liquid-state NMR | Topic: Instrumentation
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Magn. Reson., 1, 105–113, https://doi.org/10.5194/mr-1-105-2020,https://doi.org/10.5194/mr-1-105-2020, 2020
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Cited articles

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Ardenkjaer-Larsen, J. H.: On the present and future of dissolution-DNP, J. Magn. Reson., 264, 3–12, https://doi.org/10.1016/j.jmr.2016.01.015, 2016. 
Ardenkjaer-Larsen, J. H.: Hyperpolarized MR – What's up Doc?, J. Magn. Reson., 306, 124–127, https://doi.org/10.1016/j.jmr.2019.07.017, 2019. 
Ardenkjær-Larsen, J. H., Fridlund, B., Gram, A., Hansson, G., Hansson, L., Lerche, M. H., Servin, R., Thaning, M., and Golman, K.: Increase in signal-to-noise ratio of > 10 000 times in liquid-state NMR, Proc. Natl. Acad. Sci., 100, 10158–10163, https://doi.org/10.1073/pnas.1733835100, 2003. 
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Short summary
Typically, low-field Overhauser dynamic nuclear polarization (ODNP) experiments are 1D NMR experiments to study hydration dynamics. Here, we demonstrate the application of ODNP-enhanced 2D J-resolved (JRES) spectroscopy to improve spectral resolution beyond the limit imposed by the line broadening introduced by the paramagnetic polarizing agent. Crucial to these experiments is interleaved spectral referencing to compensate for temperature-induced field drifts over the course of the experiment.