Toulouse Biotechnology Institute (TBI), Université de Toulouse,
CNRS, INRAE, INSA, Toulouse, France
Neil Cox
Toulouse Biotechnology Institute (TBI), Université de Toulouse,
CNRS, INRAE, INSA, Toulouse, France
Sophie Martine Prud'homme
Université de Reims Champagne-Ardenne (URCA), UMR-I 02 SEBIO
(Stress Environnementaux et Biosurveillance des milieux aquatiques), Moulin
de la Housse, Reims, France
present address: Université de Lorraine, CNRS, LIEC, 57000, Metz, France
Alain Geffard
Université de Reims Champagne-Ardenne (URCA), UMR-I 02 SEBIO
(Stress Environnementaux et Biosurveillance des milieux aquatiques), Moulin
de la Housse, Reims, France
Institute for Biological Interfaces 4 – Magnetic Resonance,
Karlsruhe Institute of Technology (KIT), Herrmann-von-Helmholtz-Platz 1,
76344 Eggenstein-Leopoldshafen, Germany
The HSQC experiment developed by Bodenhausen and Ruben is a cornerstone for modern NMR. When used in the field of metabolomics, the common practice of decoupling in the proton dimension limits the acquisition time and hence the resolution. Here, we present a virtual decoupling method to maintain both spectral simplicity and resolution, and demonstrate how it increases information content with the zebra mussel metabolome as an example.
The HSQC experiment developed by Bodenhausen and Ruben is a cornerstone for modern NMR. When...
