Articles | Volume 2, issue 2
https://doi.org/10.5194/mr-2-653-2021
https://doi.org/10.5194/mr-2-653-2021
Research article
 | 
20 Aug 2021
Research article |  | 20 Aug 2021

A novel multinuclear solid-state NMR approach for the characterization of kidney stones

César Leroy, Laure Bonhomme-Coury, Christel Gervais, Frederik Tielens, Florence Babonneau, Michel Daudon, Dominique Bazin, Emmanuel Letavernier, Danielle Laurencin, Dinu Iuga, John V. Hanna, Mark E. Smith, and Christian Bonhomme

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Field: Solid-state NMR | Topic: Applications – materials
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Cited articles

Bak, M., Thomsen, J. K., Jakobsen, H. J., Petersen, S. E., Petersen, T. E., and Nielsen, N. C.: Solid-state 13C and 31P NMR analysis of urinary stones, J. Urol., 164, 856–863, https://doi.org/10.1016/S0022-5347(05)67327-2, 2000. 
Basso, R., Lucchetti, G., Zefiro, L., and Palenzona, A.: Caoxite, Ca(H2O)3 (C2O4), a new mineral from the Cherchiara mine, northern Apennines, Italy, Neues Jb. Miner. Monat., 2, 84–96, https://doi.org/10.1127/njmm/1997/1997/84, 1997. 
Bazin, D., Daudon, M., Combes, C., and Rey, C.: Characterization and some physicochemical aspects of pathological microcalcifications, Chem. Rev., 112, 5092–5120, https://doi.org/10.1021/cr200068d, 2012. 
Bazin, D., Haymann, J.-P., and Letavernier, E.: From urolithiasis to pathological calcification: a journey at the interface between physics, chemistry and medicine. A tribute to Michel Daudon, C.R. Chim., 19, 1388, https://doi.org/10.1016/j.crci.2016.10.001, 2016. 
Bazin, D., Letavernier, E., Haymann, J.-P., Frochot, V., and Daudon, M.: Crystalline pathologies in the human body: first steps of pathogenesis, Ann. Biol. Clin.-Paris, 78, 349–362, https://doi.org/10.1684/abc.2020.1557, 2020. 
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Short summary
Kidney stones (KSs) are a major health problem in industrialized countries. The study of KSs is presently at the heart of a concerted multidisciplinary axis of research involving physicians, physical chemists and spectroscopists. In this contribution, an in-depth structural description of KSs is proposed by implementing a combination of multinuclear and multidimensional solid-state NMR methodology.