Articles | Volume 2, issue 2
Magn. Reson., 2, 815–825, 2021
https://doi.org/10.5194/mr-2-815-2021

Special issue: Geoffrey Bodenhausen Festschrift

Magn. Reson., 2, 815–825, 2021
https://doi.org/10.5194/mr-2-815-2021

Research article 11 Nov 2021

Research article | 11 Nov 2021

A cryogen-free, semi-automated apparatus for bullet-dynamic nuclear polarization with improved resolution

Karel Kouřil et al.

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Interactive discussion

Status: closed

Comment types: AC – author | RC – referee | CC – community | EC – editor | CEC – chief editor | : Report abuse
  • RC1: 'Comment on mr-2021-57', Anonymous Referee #1, 05 Aug 2021
  • RC2: 'Comment on mr-2021-57', Anonymous Referee #2, 05 Sep 2021
  • AC1: 'Comment on mr-2021-57', Benno Meier, 08 Oct 2021

Peer review completion

AR: Author's response | RR: Referee report | ED: Editor decision
AR by Benno Meier on behalf of the Authors (12 Oct 2021)  Author's response    Author's tracked changes    Manuscript
ED: Publish as is (20 Oct 2021) by Daniel Abergel
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Short summary
The signals that are attainable in conventional NMR are tiny, and consequentially, NMR is often slow and insensitive. The intensity may be increased by hyperpolarization, provided that the spectral quality is essentially preserved. We have recently reported a potentially powerful hyperpolarization scheme, named bullet-DNP (dynamic nuclear polarization). Here, we report a 10-fold improvement in resolution for that method, which may enable new applications in metabolomics and drug discovery.