Articles | Volume 4, issue 1
https://doi.org/10.5194/mr-4-47-2023
https://doi.org/10.5194/mr-4-47-2023
Research article
 | 
16 Feb 2023
Research article |  | 16 Feb 2023

Paramagnetic relaxivity of delocalized long-lived states of protons in chains of CH2 groups

Aiky Razanahoera, Anna Sonnefeld, Geoffrey Bodenhausen, and Kirill Sheberstov

Related authors

Simulation of NMR spectra at zero and ultralow fields from A to Z – a tribute to Prof. Konstantin L'vovich Ivanov
Quentin Stern and Kirill Sheberstov
Magn. Reson., 4, 87–109, https://doi.org/10.5194/mr-4-87-2023,https://doi.org/10.5194/mr-4-87-2023, 2023
Short summary
In memoriam Konstantin L'vovich Ivanov
Alexandra Yurkovskaya and Geoffrey Bodenhausen
Magn. Reson., 2, 341–342, https://doi.org/10.5194/mr-2-341-2021,https://doi.org/10.5194/mr-2-341-2021, 2021
Short summary
Open Access: Strengths, Weaknesses, Opportunities, and Threats. An Editorial
Geoffrey Bodenhausen
Magn. Reson. Discuss., https://doi.org/10.5194/mr-2020-28,https://doi.org/10.5194/mr-2020-28, 2020
Revised manuscript not accepted
Spatio-temporal encoding by quadratic gradients in magnetic resonance imaging
Sina Marhabaie, Geoffrey Bodenhausen, and Philippe Pelupessy
Magn. Reson. Discuss., https://doi.org/10.5194/mr-2019-2,https://doi.org/10.5194/mr-2019-2, 2019
Preprint withdrawn
Short summary

Related subject area

Field: Liquid-state NMR | Topic: (Bio)Chemistry
Cell-free synthesis of proteins with selectively 13C-labelled methyl groups from inexpensive precursors
Damian Van Raad, Gottfried Otting, and Thomas Huber
Magn. Reson., 4, 187–197, https://doi.org/10.5194/mr-4-187-2023,https://doi.org/10.5194/mr-4-187-2023, 2023
Short summary

Cited articles

Ardenkjær-Larsen, J. H., Fridlund, B., Gram, A., Hansson, G., Hansson, L., Lerche, M. H., Servin, R., Thaning, M., and Golman, K.: Increase in signal-to-noise ratio of > 10,000 times in liquid-state NMR, P. Natl. Acad. Sci. USA, 100, 10158–10163, https://doi.org/10.1073/pnas.1733835100, 2003. 
Bengs, C. and Levitt, M. H.: SpinDynamica: Symbolic and numerical magnetic resonance in a Mathematica environment, Magn. Reson. Chem., 56, 374–414, https://doi.org/10.1002/mrc.4642, 2018. 
Borah, B. and Bryant, R. G.: NMR relaxation dispersion in an aqueous nitroxide system, J. Chem. Phys., 75, 3297–3300, https://doi.org/10.1063/1.442480, 1981. 
Bornet, A., Ji, X., Mammoli, D., Vuichoud, B., Milani, J., Bodenhausen, G., and Jannin, S.: Long-Lived States of Magnetically Equivalent Spins Populated by Dissolution-DNP and Revealed by Enzymatic Reactions, Eur. J. Chem., 20, 17113–17118, https://doi.org/10.1002/chem.201404967, 2014. 
Buratto, R., Bornet, A., Milani, J., Mammoli, D., Vuichoud, B., Salvi, N., Singh, M., Laguerre, A., Passemard, S., Gerber-Lemaire, S., Jannin, S., and Bodenhausen, G.: Drug Screening Boosted by Hyperpolarized Long-Lived States in NMR, ChemMedChem, 9, 2509–2515, https://doi.org/10.1002/cmdc.201402214, 2014a. 
Download
Short summary
In this work, we study the relaxivity of long-lived states (LLSs) excited across two to three CH2 groups in four different compounds and find that a commonly used polarising agent in dissolution dynamic nuclear polarization (d-DNP) does not enhance relaxation significantly. This result is important for the future implementation of d-DNP hyperpolarization of LLS.