Buratto, R., Mammoli, D., Chiarparin, E., Williams, G., and Bodenhausen, G.:
Exploring Weak Ligand–Protein Interactions by Long-Lived NMR States:
Improved Contrast in Fragment-Based Drug Screening, Angew. Chem. Int. Edit.,
53, 11376–11380, https://doi.org/10.1002/anie.201404921, 2014b.
Buratto, R., Mammoli, D., Canet, E., and Bodenhausen, G.: Ligand–Protein
Affinity Studies Using Long-Lived States of Fluorine-19 Nuclei, J. Med.
Chem., 59, 1960–1966, https://doi.org/10.1021/acs.jmedchem.5b01583, 2016.
Carravetta, M. and Levitt, M. H.: Long-Lived Nuclear Spin States in
High-Field Solution NMR, J. Am. Chem. Soc., 126, 6228–6229,
https://doi.org/10.1021/ja0490931, 2004.
Carravetta, M., Johannessen, O. G., and Levitt, M. H.: Beyond the T1 Limit:
Singlet Nuclear Spin States in Low Magnetic Fields, Phys. Rev. Lett., 92,
153003, https://doi.org/10.1103/PhysRevLett.92.153003, 2004.
DeVience, S. J., Walsworth, R. L., and Rosen, M. S.: Preparation of Nuclear
Spin Singlet States Usin
g Spin-Lock Induced Crossing, Phys. Rev. Lett., 111,
173002, https://doi.org/10.1103/PhysRevLett.111.173002, 2013.
Eichhorn, T. R., Takado, Y., Salameh, N., Capozzi, A., Cheng, T., Hyacinthe,
J.-N., Mishkovsky, M., Roussel, C., and Comment, A.: Hyperpolarization
without persistent radicals for in vivo real-time metabolic imaging, P. Natl. Acad. Sci. USA,
110, 18064–18069, https://doi.org/10.1073/pnas.1314928110, 2013.
El Daraï, T., Cousin, S. F., Stern, Q., Ceillier, M., Kempf, J.,
Eshchenko, D., Melzi, R., Schnell, M., Gremillard, L., Bornet, A., Milani,
J., Vuichoud, B., Cala, O., Montarnal, D., and Jannin, S.: Porous
functionalized polymers enable generating and transporting hyperpolarized
mixtures of metabolites, Nat. Commun., 12, 4695,
https://doi.org/10.1038/s41467-021-24279-2, 2021.
Elliott, S. J., Kadeøávek, P., Brown, L. J., Sabba, M., Glöggler,
S., O'Leary, D. J., Brown, R. C. D., Ferrage, F., and Levitt, M. H.:
Field-cycling long-lived-state NMR of
15N
2 spin pairs, Mol. Phys., 117,
861–867, https://doi.org/10.1080/00268976.2018.1543906, 2019.
Erriah, B. and Elliott, S. J.: Experimental evidence for the role of
paramagnetic oxygen concentration on the decay of long-lived nuclear spin
order, RSC Adv., 9, 23418–23424, https://doi.org/10.1039/C9RA03748A, 2019.
Feng, Y., Theis, T., Liang, X., Wang, Q., Zhou, P., and Warren, W. S.:
Storage of Hydrogen Spin Polarization in Long-Lived
13C
2 Singlet Order and
Implications for Hyperpolarized Magnetic Resonance Imaging, J. Am. Chem.
Soc., 135, 9632–9635, https://doi.org/10.1021/ja404936p, 2013.
Franzoni, M. B., Buljubasich, L., Spiess, H. W., and Münnemann, K.:
Long-Lived
1H Singlet Spin States Originating from Para-Hydrogen in
Cs-Symmetric Molecules Stored for Minutes in High Magnetic Fields, J. Am.
Chem. Soc., 134, 10393–10396, https://doi.org/10.1021/ja304285s, 2012.
Gajan, D., Bornet, A., Vuichoud, B., Milani, J., Melzi, R., van Kalkeren, H.
A., Veyre, L., Thieuleux, C., Conley, M. P., Grüning, W. R.,
Schwarzwälder, M., Lesage, A., Copéret, C., Bodenhausen, G., Emsley,
L., and Jannin, S.: Hybrid polarizing solids for pure hyperpolarized liquids
through dissolution dynamic nuclear polarization, P. Natl. Acad. Sci. USA, 111, 14693–14697,
https://doi.org/10.1073/pnas.1407730111, 2014.
Hogben, H. J., Hore, P. J., and Kuprov, I.: Multiple decoherence-free states
in multi-spin systems, J. Magn. Reson., 211, 217–220,
https://doi.org/10.1016/j.jmr.2011.06.001, 2011.
Ji, X., Bornet, A., Vuichoud, B., Milani, J., Gajan, D., Rossini, A. J.,
Emsley, L., Bodenhausen, G., and Jannin, S.: Transportable hyperpolarized
metabolites, Nat. Commun., 8, 13975, https://doi.org/10.1038/ncomms13975,
2017.
Kharkov, B., Duan, X., Rantaharju, J., Sabba, M., Levitt, M. H., Canary, J.
W., and Jerschow, A.: Weak nuclear spin singlet relaxation mechanisms
revealed by experiment and computation, Phys. Chem. Chem. Phys., 24,
7531–7538, https://doi.org/10.1039/D1CP05537B, 2022.
Kim, Y., Liu, M., and Hilty, C.: Parallelized Ligand Screening Using
Dissolution Dynamic Nuclear Polarization, Anal. Chem., 88, 11178–11183,
https://doi.org/10.1021/acs.analchem.6b03382, 2016.
Kiryutin, A. S., Rodin, B. A., Yurkovskaya, A. V., Ivanov, K. L., Kurzbach,
D., Jannin, S., Guarin, D., Abergel, D., and Bodenhausen, G.: Transport of
hyperpolarized samples in dissolution-DNP experiments, Phys. Chem. Chem.
Phys., 21, 13696–13705, https://doi.org/10.1039/C9CP02600B, 2019.
Kouøil, K., Kouøilová, H., Bartram, S., Levitt, M. H., and Meier,
B.: Scalable dissolution-dynamic nuclear polarization with rapid transfer of
a polarized solid, Nat. Commun., 10, 1733,
https://doi.org/10.1038/s41467-019-09726-5, 2019.
Kress, T., Walrant, A., Bodenhausen, G., and Kurzbach, D.: Long-Lived States
in Hyperpolarized Deuterated Methyl Groups Reveal Weak Binding of Small
Molecules to Proteins, J. Phys. Chem. Lett., 10, 1523–1529,
https://doi.org/10.1021/acs.jpclett.9b00149, 2019.
Lee, Y., Zeng, H., Ruedisser, S., Gossert, A. D., and Hilty, C.: Nuclear
Magnetic Resonance of Hyperpolarized Fluorine for Characterization of
Protein–Ligand Interactions, J. Am. Chem. Soc., 134, 17448–17451,
https://doi.org/10.1021/ja308437h, 2012.
Miéville, P., Ahuja, P., Sarkar, R., Jannin, S., Vasos, P. R.,
Gerber-Lemaire, S., Mishkovsky, M., Comment, A., Gruetter, R., Ouari, O.,
Tordo, P., and Bodenhausen, G.: Scavenging Free Radicals To Preserve
Enhancement and Extend Relaxation Times in NMR using Dynamic Nuclear
Polarization, Angew. Chem. Int. Edit., 49, 6182–6185,
https://doi.org/10.1002/anie.201000934, 2010.
Miéville, P., Jannin, S., and Bodenhausen, G.: Relaxometry of
insensitive nuclei: Optimizing dissolution dynamic nuclear polarization, J.
Magn. Reson., 210, 137–140, https://doi.org/10.1016/j.jmr.2011.02.006,
2011.
Negroni, M., Turhan, E., Kress, T., Ceillier, M., Jannin, S., and Kurzbach,
D.: Frémy's Salt as a Low-Persistence Hyperpolarization Agent: Efficient
Dynamic Nuclear Polarization Plus Rapid Radical Scavenging, J. Am. Chem.
Soc., 144, 20680–20686, https://doi.org/10.1021/jacs.2c07960, 2022.
Nelson, S. J., Kurhanewicz, J., Vigneron, D. B., Larson, P. E. Z.,
Harzstark, A. L., Ferrone, M., van Criekinge, M., Chang, J. W., Bok, R.,
Park, I., Reed, G., Carvajal, L., Small, E. J., Munster, P., Weinberg, V.
K., Ardenkjaer-Larsen, J. H., Chen, A. P., Hurd, R. E., Odegardstuen, L.-I.,
Robb, F. J., Tropp, J., and Murray, J. A.: Metabolic Imaging of Patients
with Prostate Cancer Using Hyperpolarized [1-13C]Pyruvate, Sci. Transl.
Med., 5, 198ra108, https://doi.org/10.1126/scitranslmed.3006070, 2013.
Pileio, G., Hill-Cousins, J. T., Mitchell, S., Kuprov, I., Brown, L. J.,
Brown, R. C. D., and Levitt, M. H.: Long-Lived Nuclear Singlet Order in
Near-Equivalent
13C Spin Pairs, J. Am. Chem. Soc., 134, 17494–17497,
https://doi.org/10.1021/ja3089873, 2012.
Razanahoera, A., Sonnefeld, A., Bodenhausen, G., and Sheberstov, K.: Paramagnetic relaxivity of delocalized long-lived states of protons in chains of CH
2 groups, Zenodo [data set], https://doi.org/10.5281/zenodo.7432635, 2022.
Salvi, N., Buratto, R., Bornet, A., Ulzega, S., Rentero Rebollo, I.,
Angelini, A., Heinis, C., and Bodenhausen, G.: Boosting the Sensitivity of
Ligand–Protein Screening by NMR of Long-Lived States, J. Am. Chem. Soc.,
134, 11076–11079, https://doi.org/10.1021/ja303301w, 2012.
Sarkar, R., Vasos, P. R., and Bodenhausen, G.: Singlet-State Exchange NMR
Spectroscopy for the Study of Very Slow Dynamic Processes, J. Am. Chem.
Soc., 129, 328–334, https://doi.org/10.1021/ja0647396, 2007.
Sheberstov, K. F., Vieth, H.-M., Zimmermann, H., Rodin, B. A., Ivanov, K.
L., Kiryutin, A. S., and Yurkovskaya, A. V.: Generating and sustaining
long-lived spin states in
15N,
15N'-azobenzene, Sci. Rep., 9, 20161, https://doi.org/10.1038/s41598-019-56734-y, 2019.
Sonnefeld, A., Razanahoera, A., Pelupessy, P., Bodenhausen, G., and
Sheberstov, K.: Long-lived states of methylene protons in achiral molecules,
Sci. Adv., 8, eade2113, https://doi.org/10.1126/sciadv.ade2113, 2022a.
Sonnefeld, A., Bodenhausen, G., and Sheberstov, K.: Polychromatic Excitation
of Delocalized Long-Lived Proton Spin States in Aliphatic Chains, Phys. Rev.
Lett., 129, 183203, https://doi.org/10.1103/PhysRevLett.129.183203, 2022b.
Stevanato, G., Hill-Cousins, J. T., Håkansson, P., Roy, S. S., Brown, L.
J., Brown, R. C. D., Pileio, G., and Levitt, M. H.: A Nuclear Singlet
Lifetime of More than One Hour in Room-Temperature Solution, Angew. Chem.
Int. Edit., 54, 3740–3743, https://doi.org/10.1002/anie.201411978, 2015.
Tayler, M. C. D.: Chapter 10: Filters for Long-lived Spin Order, in:
Long-lived Nuclear Spin Order, edited by: Pileio, G., RSC publishing, 188–208,
https://books.rsc.org/books/edited-volume/850/chapter-abstract/599446/Filters-for-Long-lived-Spin-Order?redirectedFrom=fulltext (last access: 14 February 2023), 2020.
Tayler, M. C. D. and Levitt, M. H.: Accessing Long-Lived Nuclear Spin Order
by Isotope-Induced Symmetry Breaking, J. Am. Chem. Soc., 135, 2120–2123,
https://doi.org/10.1021/ja312227h, 2013.
Tayler, M. C. D., Marco-Rius, I., Kettunen, M. I., Brindle, K. M., Levitt,
M. H., and Pileio, G.: Direct Enhancement of Nuclear Singlet Order by
Dynamic Nuclear Polarization, J. Am. Chem. Soc., 134, 7668–7671,
https://doi.org/10.1021/ja302814e, 2012.
Wokaun, A. and Ernst, R. R.: The use of multiple quantum transitions for
relaxation studies in coupled spin systems, Mol. Phys., 36, 317–341,
https://doi.org/10.1080/00268977800101601, 1978.