Articles | Volume 6, issue 2
https://doi.org/10.5194/mr-6-273-2025
© Author(s) 2025. This work is distributed under
the Creative Commons Attribution 4.0 License.
the Creative Commons Attribution 4.0 License.
https://doi.org/10.5194/mr-6-273-2025
© Author(s) 2025. This work is distributed under
the Creative Commons Attribution 4.0 License.
the Creative Commons Attribution 4.0 License.
Research article
| 
24 Nov 2025
Research article |
| 24 Nov 2025
| 24 Nov 2025
Long-lived states involving a manifold of fluorine-19 spins in fluorinated aliphatic chains
Coline Wiame
Chimie Physique et Chimie du Vivant (CPCV, UMR 8228), Department of Chemistry, Ecole Normale Supérieure, PSL University, Sorbonne University, CNRS, Paris, 75005, France
Sebastiaan Van Dyck
Chimie Physique et Chimie du Vivant (CPCV, UMR 8228), Department of Chemistry, Ecole Normale Supérieure, PSL University, Sorbonne University, CNRS, Paris, 75005, France
Kirill Sheberstov
CORRESPONDING AUTHOR
Chimie Physique et Chimie du Vivant (CPCV, UMR 8228), Department of Chemistry, Ecole Normale Supérieure, PSL University, Sorbonne University, CNRS, Paris, 75005, France
Aiky Razanahoera
Chimie Physique et Chimie du Vivant (CPCV, UMR 8228), Department of Chemistry, Ecole Normale Supérieure, PSL University, Sorbonne University, CNRS, Paris, 75005, France
Geoffrey Bodenhausen
Chimie Physique et Chimie du Vivant (CPCV, UMR 8228), Department of Chemistry, Ecole Normale Supérieure, PSL University, Sorbonne University, CNRS, Paris, 75005, France
Related authors
Sebastiaan Van Dyck, Coline Wiame, Kirill F. Sheberstov, and Geoffrey Bodenhausen
Magn. Reson. Discuss., https://doi.org/10.5194/mr-2026-5, https://doi.org/10.5194/mr-2026-5, 2026
Preprint under review for MR
Short summary
Short summary
It is shown that proton long-lived states can be observed on benchtop NMR spectrometers in molecules containing short aliphatic chains. The effects of strong coupling between methylene groups can be mitigated by optimizing the amplitude and duration of the excitation pulse.
Sebastiaan Van Dyck, Coline Wiame, Kirill F. Sheberstov, and Geoffrey Bodenhausen
Magn. Reson. Discuss., https://doi.org/10.5194/mr-2026-5, https://doi.org/10.5194/mr-2026-5, 2026
Preprint under review for MR
Short summary
Short summary
It is shown that proton long-lived states can be observed on benchtop NMR spectrometers in molecules containing short aliphatic chains. The effects of strong coupling between methylene groups can be mitigated by optimizing the amplitude and duration of the excitation pulse.
Quentin Stern and Kirill Sheberstov
Magn. Reson., 4, 87–109, https://doi.org/10.5194/mr-4-87-2023, https://doi.org/10.5194/mr-4-87-2023, 2023
Short summary
Short summary
This tutorial paper shows how to simulate NMR spectra at zero to ultralow fields. The process is presented in detail, including the tricks that are usually omitted from research papers and assuming as little prior knowledge from the reader as possible. In this attempt to make NMR simulation approachable, the authors wish to pay tribute to the late Prof. Konstantin L’vovich Ivanov.
Aiky Razanahoera, Anna Sonnefeld, Geoffrey Bodenhausen, and Kirill Sheberstov
Magn. Reson., 4, 47–56, https://doi.org/10.5194/mr-4-47-2023, https://doi.org/10.5194/mr-4-47-2023, 2023
Short summary
Short summary
In this work, we study the relaxivity of long-lived states (LLSs) excited across two to three CH2 groups in four different compounds and find that a commonly used polarising agent in dissolution dynamic nuclear polarization (d-DNP) does not enhance relaxation significantly. This result is important for the future implementation of d-DNP hyperpolarization of LLS.
Alexandra Yurkovskaya and Geoffrey Bodenhausen
Magn. Reson., 2, 341–342, https://doi.org/10.5194/mr-2-341-2021, https://doi.org/10.5194/mr-2-341-2021, 2021
Short summary
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Short summary
In achiral polyfluoroalkyl substances with two to three CF₂ groups, long-lived ¹⁹F spin states (TLLS) were measured and found to last about three times longer than T₁ in a static 11.6 T field. These lifetimes are sensitive to macromolecular binding, making them useful for screening fluorinated drugs.
In achiral polyfluoroalkyl substances with two to three CF₂ groups, long-lived ¹⁹F spin...
