Articles | Volume 2, issue 1
https://doi.org/10.5194/mr-2-409-2021
https://doi.org/10.5194/mr-2-409-2021
Research article
 | 
11 Jun 2021
Research article |  | 11 Jun 2021

129Xe ultra-fast Z spectroscopy enables micromolar detection of biosensors on a 1 T benchtop spectrometer

Kévin Chighine, Estelle Léonce, Céline Boutin, Hervé Desvaux, and Patrick Berthault

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Latest update: 13 Apr 2024
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Short summary
The use of hyperpolarized species, i.e., species whose nuclear polarization is transiently multiplied by several orders of magnitude, can perfectly be combined with the use of benchtop NMR spectrometers. In particular, laser-polarized 129Xe, due to its large chemical shift range and the proximity of its resonance frequency to 13C, can be observed on a non-dedicated low-field spectrometer. Detection of low amounts of molecules can be achieved using NMR techniques based on chemical exchange.