Articles | Volume 2, issue 1
Research article
15 Jun 2021
Research article |  | 15 Jun 2021

Extended Bloch–McConnell equations for mechanistic analysis of hyperpolarized 13C magnetic resonance experiments on enzyme systems

Thomas R. Eykyn, Stuart J. Elliott, and Philip W. Kuchel


Interactive discussion

Status: closed

Comment types: AC – author | RC – referee | CC – community | EC – editor | CEC – chief editor | : Report abuse
  • RC1: 'Comment on mr-2021-14', Anonymous Referee #1, 07 Mar 2021
  • RC2: 'Comment on mr-2021-14', Paul Vasos, 16 Mar 2021

Peer review completion

AR: Author's response | RR: Referee report | ED: Editor decision
AR by Thomas Eykyn on behalf of the Authors (30 Mar 2021)  Author's response    Author's tracked changes    Manuscript
ED: Publish as is (08 Apr 2021) by Daniel Abergel

Post-review adjustments

AA: Author's adjustment | EA: Editor approval
AA by Thomas Eykyn on behalf of the Authors (27 Apr 2021)   Author's adjustment   Manuscript
EA: Adjustments approved (06 May 2021) by Daniel Abergel
Short summary
An approach is described for formulating the kinetic master equations of the time evolution of hyperpolarized NMR signals in reacting (bio)chemical systems. We take a stepwise approach to formulate mathematical models of enzyme systems that agree with standard descriptions of (bio)chemical kinetics while remaining capable of describing the time evolution of magnetization described by the Bloch–McConnell equations.