Articles | Volume 4, issue 1
https://doi.org/10.5194/mr-4-115-2023
https://doi.org/10.5194/mr-4-115-2023
Research article
 | 
12 May 2023
Research article |  | 12 May 2023

Time-domain proton-detected local-field NMR for molecular structure determination in complex lipid membranes

Anika Wurl, Kay Saalwächter, and Tiago Mendes Ferreira

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Latest update: 22 Jul 2024
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Short summary
R-proton-detected local-field NMR is a powerful method to obtain structural information from biological membrane models. However, the conventional analysis of experiments, by using a Fourier transform in the indirect time-domain and reading-off splittings, is unsuitable to investigate complex systems. One then needs to model the experimental data. Fitting the experimental data with simulations that account for radiofrequency field inhomogeneity enables accurate modeling of R-PDLF data.