Articles | Volume 4, issue 1
Research article
15 Mar 2023
Research article |  | 15 Mar 2023

Multidimensional encoding of restricted and anisotropic diffusion by double rotation of the q vector

Hong Jiang, Leo Svenningsson, and Daniel Topgaard


Interactive discussion

Status: closed

Comment types: AC – author | RC – referee | CC – community | EC – editor | CEC – chief editor | : Report abuse
  • CC1: 'Comment on mr-2022-16', Tom Barbara, 17 Oct 2022
  • RC1: 'Comment on mr-2022-16', Tom Barbara, 08 Nov 2022
    • RC2: 'Reply on RC1', Tom Barbara, 09 Nov 2022
      • RC3: 'Reply on RC2', Tom Barbara, 15 Nov 2022
  • RC4: 'Comment on mr-2022-16', Anonymous Referee #2, 01 Jan 2023
    • RC5: 'Reply on RC4', Tom Barbara, 03 Jan 2023
  • AC1: 'Comment on mr-2022-16', Daniel Topgaard, 08 Feb 2023

Peer review completion

AR: Author's response | RR: Referee report | ED: Editor decision | EF: Editorial file upload
AR by Daniel Topgaard on behalf of the Authors (08 Feb 2023)  Author's response   Author's tracked changes   Manuscript 
EF by Lisa Appel (09 Feb 2023)  Supplement 
ED: Publish as is (11 Feb 2023) by Kong Ooi Tan
AR by Daniel Topgaard on behalf of the Authors (13 Feb 2023)

Post-review adjustments

AA: Author's adjustment | EA: Editor approval
AA by Daniel Topgaard on behalf of the Authors (14 Mar 2023)   Author's adjustment   Manuscript
EA: Adjustments approved (14 Mar 2023) by Kong Ooi Tan
Short summary
Diffusion MRI is a clinically important tool for noninvasive detection of pathological conditions that lead to microscopic changes in cell and tissue structures, but this technique suffers from interpretational ambiguities when applied to heterogeneous and disordered tissues comprising cells with multiple sizes, shapes, and orientations. We propose a simple scheme to encode the MRI signal with a sufficient amount of information to resolve and study all properties simultaneously.